Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 680 clinical trials
Randomised Evaluation of COVID-19 Therapy

RECOVERY is a randomised trial investigating whether treatment with either Lopinavir-Ritonavir, Hydroxychloroquine, Corticosteroids, Azithromycin, Convalescent plasma or Tocilizumab prevents death in patients with COVID-19.

acute respiratory syndrome (sars)
covid-19
azithromycin
hydroxychloroquine
immunoglobulin
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Home-based Physical Activity Programme for Patients With Advanced Interstitial Lung Diseases (iLiFE)

Interstitial lung diseases (ILD) are a highly incapacitating group of chronic respiratory diseases, leading to disabling symptoms and impaired capacity to perform activities of daily living and health-related quality of life (HRQoL).

  • 0 views
  • 19 Feb, 2024
  • 1 location
Connexin Genotypes in Cystic Fibrosis

Background: There is wide variety in lung disease phenotype for the delta F508 (homozygous) genotype. A leukocyte driven inflammation is most important for the pathogenesis of pulmonary disease in CF.

fibrosis
prednisone
forced expiratory volume
lung transplant
pulmonary function test
  • 0 views
  • 19 Feb, 2024
  • 3 locations
ELUCIDATE: Enabling LUng Cancer IDentification Using folATE Receptor Targeting

This is a phase 3, multi-center, single dose, open-label, exploratory study in suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/PET/MRI or other imaging based on standard of care. This study aims to assess the efficacy of OTL38 and Near Infrared Imaging (NIR) at identifying pulmonary …

cancer
pulmonary resection
thoracic surgery
lung cancer
wedge excision
  • 0 views
  • 19 Feb, 2024
  • 5 locations
cfDNA Methylation Assay for Clinical Evaluation of Patients With Stage IA Lung Cancer After Ablation Operation

The objective is to screen and monitor the efficacy of cfDNA methylation in patients with stage I lung cancer after ablation, to compare the similarities and differences of cfDNA methylation between surgical treatment and ablation in patients with stage I lung cancer, and to look for new indicators to assess …

cancer
ct scan chest
cfdna
lung cancer
chest ct
  • 0 views
  • 19 Feb, 2024
  • 1 location
Lung Surgery With Enhanced Recovery VS. Lung Surgery Without Enhanced Recovery

Objective: The adoption of Enhanced Recovery Surgery programs in lung resection is relatively recent with limited outcome data. This study aimed to determine the impact of an Enhanced Recovery Surgery pathway on short- term and long- term results in patients undergoing lung resection for primary lung cancer.

cancer
pulmonary resection
enhanced recovery after surgery
lung operation
lung surgery
  • 18 views
  • 19 Feb, 2024
  • 1 location
Doxapram Therapy in Preterm Infants (DOXA Trial)

This study compares doxapram to placebo and hypothesizes that doxapram will protect preterm infants from both invasive ventilation (and related lung disease) and AOP related oxygen shortage (and related impaired brain development).

lung disease
off-label
apnea
doxapram
pulmonary disease
  • 0 views
  • 19 Feb, 2024
  • 18 locations
Bovine Reinforcement in Stomach, Colorectal and Lung Operation (123)

The primary purpose of this prospective, randomized multicenter center study is to evaluate and compare the outcomes of stomach,colorectal and lung anastomoses reinforced with a bioabsorbable staple line reinforcement material compared with standard non-reinforced techniques with respect to the incidence of postoperative hemorrage rate, anastomotic leakage, if applicable.

  • 0 views
  • 14 May, 2025
  • 1 location
Clinical Utility of Liquid Biopsy in Brigatinib ALK+ Patients

Chemotherapy-nave patients with EML4-ALK rearrangement and with locally advanced or metastatic non-small cell lung cancer patients will be selected. Patients enrolled in the study will receive brigatinib 90mg for the first 7 days (D 1-7 at cycle 1) and then 180mg daily thereafter for QW4 cycles of duration (28 days …

hepatitis b surface antigen
brigatinib
cns metastases
stage iv non-small cell lung cancer
aptt
  • 0 views
  • 19 Feb, 2024
  • 15 locations
SBRT Dose Escalation for Reirradiation of Inoperable Lung Lesions

Prospective phase I study to evaluate the maximum tolerated dose (MTD) of SBRT for thoracic re-irradiation. Dose limiting toxicity will be pneumonitis G3. The potential advantage of the dose escalation planned in this study is the delivery of an ablative dose to radically treat patients with inoperable local relapse, without …

cancer
tumor recurrence
lung cancer
small cell lung cancer
pulmonary metastasis
  • 0 views
  • 19 Feb, 2024
  • 1 location