Colorectal Neoplasms Clinical Trials

A listing of Colorectal Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 56 clinical trials
Tocotrienol and Bevacizumab in Metastatic Colorectal Cancer

This double blind, randomized phase II trial will investigate whether the addition of tocotrienol will improve the effect and lower the toxicity of standard chemotherapy and bevacizumab. Half of the patients will receive tocotrienol and the other half placebo. Treatment is planned for a period of maximum six months and …

kidney function test
serum bilirubin level
neutrophil count
oxaliplatin
tubal occlusion
  • 0 views
  • 19 Feb, 2024
Accelerating Colorectal Cancer Screening Through Implementation Science in Appalachia

colorectal cancer (CRC) screening, follow-up, and referral-to-care among patients age 50-74 in 12 counties in Appalachian Kentucky and Ohio. The 12 counties will be assigned to one of two study groups (early

colorectal cancer screening
cancer screening
colorectal cancer
screening for colorectal cancer
  • 0 views
  • 19 Feb, 2024
Efficacy of HIPEC in Patients With Colorectal Cancer at High Risk of Peritoneal Carcinomatosis

The purpose of this study is to determine the efficacy of adjuvant HIPEC with Mitomycin C after colectomy in the treatment of colorectal cancer patients at high risk of peritoneal carcinomatosis

peritoneal carcinomatosis
adjuvant
hyperthermic intraperitoneal chemotherapy
colorectal adenocarcinoma
mitomycin
  • 0 views
  • 19 Feb, 2024
S0820, Adenoma and Second Primary Prevention Trial (PACES)

The investigators hypothesize that the combination of eflornithine and sulindac will be effective in reducing the event rate of adenomas and second primary colorectal cancers at three years in

  • 0 views
  • 19 Feb, 2024
  • 1 location
Intratumoral Tilsotolimod a TLR-9 Agonist Together With Intratumoral Ipilimumab and Intravenous Nivolumab in Patients With Advanced Cancers

: immunotherapy nave microsatellite stable colorectal cancer (MSS CRC) cohort

metastasis
conventional treatment
advanced melanoma
liver metastasis
gilbert's syndrome
  • 0 views
  • 19 Feb, 2024
Fuzheng Yiliu-1010

Real world study was used to evaluate the therapeutic effect of Fuzheng anti-tumor therapy on colorectal cancer patients in stage II and III after surgery and standard chemotherapy, and the

  • 0 views
  • 19 Feb, 2024
Anesthesia and Cancer Study: Colon

This study investigates the influence of type of anesthesia on survival and recurrence rate in patients receiving colon cancer surgery. The participants will be allocated to either the TIVA group and the inhalation group.

sevoflurane
colon cancer
propofol
cancer surgery
tiva
  • 0 views
  • 19 Feb, 2024
Prospective Randomized Placebo-Controlled Trial of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE) (SURVIVE)

The primary purpose of this study is to determine whether adding SurVaxM to standard chemotherapy with temozolomide is better than treatment with temozolomide alone for patients with newly diagnosed glioblastoma. This study is designed to compare the duration of survival in patients with newly diagnosed glioblastoma receiving temozolomide plus SurVaxM …

  • 0 views
  • 19 Feb, 2024
  • 10 locations
Dose-escalation Study of APG-1387 and Toripalimab in Solid Tumors

An ascending dose study in patients with solid tumors to evaluate the safety, tolerability, pharmacodynamics and efficacy of APG-1387 in combination with toripalimab. A phase II study of 3 cohorts will be included.

metastasis
antineoplastic
alopecia
liver metastasis
neuropathy
  • 0 views
  • 19 Feb, 2024
MEK Inhibitor and a PDL1 Inhibitor Patients With Locally Advanced and/or Metastatic Soft Tissue Sarcoma

The proposed study is a two-step trial with 1) a safety run in part conducted in pediatric patients and 2) a Phase II part in adult and pediatric patients aiming to evaluate the safety and clinical activity of atezolizumab + cobimetinib in advanced/metastatic soft tissue sarcomas.

metastasis
atezolizumab
adjuvant
anthracyclines
epithelioid sarcomas
  • 0 views
  • 19 Feb, 2024