Kidney Disease Clinical Trials

A listing of Kidney Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 15 clinical trials
A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients

To evaluate the pharmacokinetics (PK) of venglustat in Autosomal Dominant Polycystic Kidney Disease patients (Stages 1 and 2). To determine the effect of venglustat on pain and fatigue, based on patient reported diary (Stages 1 and 2).

tolvaptan
autosomal dominant
antihypertensive therapy
cyst
human chorionic gonadotropin
  • 0 views
  • 19 Feb, 2024
  • 81 locations
Prospective Multicenter Non-randomized Single Arm Clinical Trial to Evaluate the Safety and Efficacy of e-PTFE Grafts Inner Surface-treated With Paclitaxel as an Access for Hemodialysis in Patients With End-stage Renal Disease.

This prospective, multicenter, non-randomized, single-arm Clinical trial aims to evaluate the safety and effectiveness of the use of paclitaxel-coated arteriovenous graft (AVG) on the inner wall of ePTFE graft, which is designed to reduce neointimal hyperplasia that causes stenosis and thrombosis after implantation of AVG.

  • 0 views
  • 19 Feb, 2024
Microbiota and Bone Fragility:Study of the Relation Between Gut Microbiota and Bone Microarchitecture

Gut microbiota regulate metabolism of their human host. Some diseases are associated with variations in gut microbiota diversity and higher fracture risk. Intestinal bacteria synthesize or influence synthesis of factors modulating bone metabolism. The link between gut microbiota and bone was assessed mainly in experimental animal studies. Clinical data, e.g. …

postmenopausal osteoporosis
spinal fracture
spinal fractures
bone mineral density
bone densitometry
  • 0 views
  • 19 Feb, 2024
ZEUS A research study to see how Ziltivekimab works compared to placebo in patients with cardiovascular disease, chronic kidney disease and inflammation (ZEUS)

The purpose of this study is to see if the new study drug, Ziltivekimab, can be used to treat people with cardiovascular disease, chronic kidney disease, and inflammation. The ZEUS study will see if Ziltivekimab can reduce the risk of having cardiovascular events (for example, heart attack and stroke).

  • 0 views
  • 19 Feb, 2024
  • 1 location
Everolimus Plus Mycophenolic Acid for Kidney Preservation in Liver Transplant Recipients With Impaired Kidney Function

Replacement of Tacrolimus by Everolimus may have a reduced incidence of renal dysfunction in liver transplant patients who already have chronic kidney disease or peri-operative acute kidney injury. Liver transplant patients receive potent induction immunosuppression in the form of rabbit anti thymocyte globulin.

antithymocyte globulin
anti-thymocyte globulin
mycophenolate mofetil
hepatitis b
chronic disease
  • 0 views
  • 19 Feb, 2024
Liberation From Acute Dialysis

The goal of the LIBERATE-D clinical trial is to improve outcomes for patients recovering from dialysis-requiring acute kidney injury (AKI-D). The impact of a conservative dialysis strategy compared to standard clinical practice of thrice-weekly dialysis will be examined to help generate knowledge for how to guide delivery of dialysis to …

acute renal failure
intermittent hemodialysis
renal replacement
dialysis
renal injury
  • 0 views
  • 19 Feb, 2024
Antibiotic Selection Using Next Generation Sequencing vs Urine Culture

This is a randomized controlled clinical study evaluating the use of next-generation sequencing (NGS) to improve antibiotic prescribing before ureteroscopy or percutaneous nephrolithotomy.

bladder stone
percutaneous nephrolithotomy
antibiotics
nephrolithotomy
stone removal
  • 0 views
  • 19 Feb, 2024
Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Localized Renal Tumor

This feasibility study will evaluate how well hyperpolarized 13C pyruvate magnetic resonance imaging (MRI) scan works in predicting tumor aggressiveness in patients with localized renal tumor. Hyperpolarized 13C pyruvate is a non-radioactive substance with potential usage in the diagnostic imaging of tumors. Hyperpolarized 13C pyruvate MRI may help doctors determine …

kidney tumor
renal neoplasm
estimated creatinine clearance
MRI
abdominal mri
  • 0 views
  • 19 Feb, 2024
Lenvatinib and Pembrolizumab Before Surgery for the Treatment of Locally Advanced Non-Metastatic Kidney Cancer

This phase II trial studies how well lenvatinib and pembrolizumab before surgery work in treating patients with kidney cancer that has spread from its original site of growth to nearby tissues or lymph nodes but has not spread to other places in the body (non-metastatic). Lenvatinib may stop the growth …

renal cell carcinoma
metastatic renal cell carcinoma
chorionic gonadotropin
aptt
azoospermia
  • 8 views
  • 19 Feb, 2024
  • 1 location
Global Kidney Patient Trials Network

This is a prospective international multi-centre, observational cohort study of incident and prevalent patients diagnosed with a kidney disease

nephropathy
  • 0 views
  • 19 Feb, 2024