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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 805 clinical trials

J Janis Cole, BSc

The Alberta NutrIMM Study - Nutrition and Immunity

Excess weight, nutrition, and blood sugar levels can all affect immune function, which in turn can affect participants risk for heart disease and type 2 diabetes (T2DM). It is not known how diet, blood sugar, and weight affect immune function. The purpose of the study is to look at how …

18-65 years All Phase N/A
N Niels Thue Olsen, MD, PhD

Balloon Lithoplasty for Preparation of Severely Calcified Coronary Lesions

Severely calcified coronary stenoses are difficult to treat with percutaneous coronary intervention (PCI) using current techniques and there is little specific evidence on how to best treat these cases. It is hypothesized that balloon lithoplasty is superior to conventional balloons for lesion preparation of severely calcified coronary lesions before stent …

18-90 years All Phase N/A
J Joachim Ehrlich, Prof. Dr.

Cryoballoon Pulmonary Vein Isolation for Atrial Fibrillation With Heart Failure

The combination of atrial fibrillation (AF) and heart failure (HF) is common and implies a poor prognosis. Pulmonary vein isolation is an established method for the treatment of symptomatic AF in patients with normal heart function and has been shown to be more effective than drug therapy. Recently, radiofrequency ablation …

18-99 years All Phase N/A
D Dulce González-Islas, PhD

Effect of Nutritional Supplementation and Pulmonary Rehabilitation on the Clinical Status of HF and COPD

Cardiovascular diseases (CVD) are the leading cause of death in the world and our country. The prevalence of Heart Failure (HF) is 1-2% in the adult population in developed countries, up to 10% among people 70 years of age. Concerning COPD, it is estimated that by 2030 will be the …

40 years and older All Phase N/A
S Samantha Fichtner, BSN, RN

Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts

A single arm clinical trial evaluating the safety and efficacy of the second generation TEVG as vascular conduits for extracardiac total cavopulmonary connection.

100 years and younger All Phase 2
M Marleen van Wely, MD

Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI

Rationale: Transcatheter aortic valve implantation (TAVI) has become the standard therapy for elderly patients with high surgical risks. Paravalvular leakage after TAVI is relatively common and there is conflicting evidence regarding the clinical impact of mild paravalvular leakage in self-expanding devices. Prospective data for self-expanding devices are required to compare …

18 years and older All Phase N/A
H Helena Lindberg, MD

Healthrelated Quality of Life and Experiences of a Heart Rehabilitation Programme After Care for Infective Endocarditis.

<p>Can the health of patients with Infective endocarditis (IE) be improved by participation in the physical exercise training within cardiac rehabilitation program?</p><p>Participants will:</p><ul><li>Be physically evaluated by a physiotherapist before and after the progam of physical exercise training within cardiac rehabilitation.</li><li>Do individual exercises in a group led by a physiotherapist 2 …

18-80 years All Phase N/A
H Helena Lindberg, MD

Healthrelated Quality of Life and Experiences of a Heart Rehabilitation Programme After Care for Infective Endocarditis.

<p>Can the health of patients with Infective endocarditis (IE) be improved by participation in the physical exercise training within cardiac rehabilitation program?</p><p>Participants will:</p><ul><li>Be physically evaluated by a physiotherapist before and after the progam of physical exercise training within cardiac rehabilitation.</li><li>Do individual exercises in a group led by a physiotherapist 2 …

18-80 years All Phase N/A
A Alberto Louro Iglesias

Effectiveness of Combining Patient Follow-Up With an Educational Intervention on Self-Management Skills of Type 2 Diabetes Mellitus Patients: A Controlled Intervention Study in Primary Care

The purpose of this clinical study is to evaluate whether patient education provided in conjunction with a structured, shared follow-up plan in primary care strengthens the self-management skills of patients with Type 2 Diabetes (T2DM). The study also aims to determine whether the effect of this intervention is associated with …

18 years and older All Phase N/A
D Daniela Sacchetti, MS

Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Alzheimer Disease

Impaired verbal communication is a cardinal symptom of Alzheimer Disease (AD) and the source of enormous distress and disability. Effective therapies for this deficit are lacking. In light of the emerging literature demonstrating that Transcranial Magnetic Stimulation (TMS) improves general cognition in subjects with Alzheimer Disease (AD), the investigators propose …

60-85 years All Phase 1

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