Parkinson's Disease Clinical Trials

A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 36 clinical trials
Sleepiness in Parkinson's Patients With Continuous Dopaminergic Delivery Device or Deep Brain Stimulation

Sleepiness is frequent in parkinsonian patients, increasing with the duration of disease. By patients with motor fluctuations, continuous dopaminergic delivery devices or deep brain stimulation are justified to improve the motor prognosis. Antiparkinsonian treatments, especially dopaminergic agonists, may worsen the sleepiness and thus affect the quality of life. We aimed …

somnolence
dopamine agonists
parkinson's disease
antiparkinsonian agents
brain stimulation
  • 0 views
  • 19 Feb, 2024
  • 1 location
LRRK2 G2385R Leucocyte and Urine Biomarker Study

Given the emerging evidence on LRRK2-related biomarkers, this project will focus on identifying leucocyte and urine biomarkers that are altered by the LRRK2 G2385R variant, and investigating the effects of LRRK2 kinase inhibitor (MLi-2) on these biomarkers, using immunoblotting and mass spectrometry.

parkinson's disease
movement disorder
  • 0 views
  • 19 Feb, 2024
  • 1 location
Neurodegenerative Diseases Registry

Due to the overlapping presentation and similar brain pathology, especially in the early stage of the diseases, it is difficult to differentiate idiopathic Parkinson's disease (iPD) from atypical parkinsonian syndromes, such as multiple system atrophy (MSA) and progressive supranuclear palsy (PSP).

alzheimer's disease
neurodegenerative disorders
parkinson's disease
motor neuron disease
brain pathology
  • 0 views
  • 19 Feb, 2024
  • 1 location
Biological Sample Collection for Research and Biobanking

The New York Stem Cell Foundation (NYSCF) is performing this research to study different conditions and diseases by using cells from the body (such as skin or blood cells). NYSCF uses these samples to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, …

genetic testing
  • 0 views
  • 19 Feb, 2024
  • 1 location
Speech Linguistic and Acoustic Markers in Parkinson's Disease

We aim to identify speech and language markers that provide information on cognitive function and predict cognitive decline in Parkinson's disease. We will administer various speech tasks and cognitive assessments to participants with Parkinson's disease and healthy controls.

cognitive impairment
mental deterioration
cognitive decline
mild cognitive impairment
parkinson's disease
  • 0 views
  • 19 Feb, 2024
  • 1 location
Comparison of Outcomes in Asleep and Awake DBS With a Directional Electrode

To compare the clinical outcome of patients with Parkinson's disease (PD) treated with directional deep brain (dDBS) stimulation undergoing subthalamic deep brain stimulation operation (STN-DBS) under general anesthesia versus local anesthesia.

tremor
general anesthesia
dyskinesia
levodopa
parkinson's disease
  • 0 views
  • 19 Feb, 2024
  • 1 location