Prospective Register on the Etiologies of Cardiogenic Shock and Their Prognosis at One Year.

STATUS

Recruiting
participants needed

1650
sponsor

Assistance Publique Hopitaux De Marseille

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Updated on 19 February 2024

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shock

vasopressor

oliguria

systolic blood pressure

hypoperfusion

heart failure

acute heart failure

hyperlactatemia

pulmonary edema

confusion

Summary

Show definitions

Cardiogenic shock (CC) is one of the major challenges of current cardiology. Despite the difficulty of establishing a strict and consensual definition, it is accepted that the CC clinically corresponds to persistent hypotension (systolic blood pressure 90 mmHg for at least 30 minutes or need for vasopressor support) associated with signs of visceral hypoperfusion (confusion, mottling, oliguria, hyperlactatemia), and hemodynamic with a lowered heart index ( 1.8 L/min/m2) despite appropriate or high filling pressures. This definition of the European Society of Cardiology (ESC) masks however the great variability of hemodynamic tables grouped under the term of CC and severity levels, also variable.However, it was suggested that the etiology of CC influenced both its hemodynamic profile and therefore its therapeutic management but also its prognosis in the medium and long term.

Description

CC diagnosis remains difficult to carry on admission and is sometimes delayed. Therefore, we would like to compare hemodynamic data from patients with CC status to those admitted for acute heart failure (ICA) to determine if a hemodynamic variable at entry would facilitate the diagnosis of CC.

Details

Condition	Cardiogenic shock
Age	18years - 100years
Clinical Study Identifier	NCT04467294
Sponsor	Assistance Publique Hopitaux De Marseille
Last Modified on	19 February 2024

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Eligibility		Yes	No	Not Sure
Inclusion Criteria
	Patients in Cardiac Shock
	mmHg hypotension or requiring inotropic or vasopressor support
	owered cardiac output ( 1.8 L/min/m2) to trans-thoracic cardiac ultrasound with high or normal filling pressures
	peripheral hypoperfusion. patients admitted for acute heart failure (ICA) (Acute pulmonary edema chart or left congestive heart failure without CC sign and with ultrasound FEVG at entry 40%.)
Exclusion Criteria
	Pregnant or nursing women
	Age 18 years
	Person of full age under guardianship
	Staying in a health or social facility
	Person not covered by a social security scheme
	Person deprived of liberty
	Shocks from other etiologies
	Patient with initial cardiac arrest
	Patient with cardiogenic shock due to right ventricular dysfunction
	Patient with pulmonary embolism
	Patient with tamponade
	Refusal to participate

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Prospective Register on the Etiologies of Cardiogenic Shock and Their Prognosis at One Year.