Prospective Register on the Etiologies of Cardiogenic Shock and Their Prognosis at One Year.

  • STATUS
    Recruiting
  • participants needed
    1650
  • sponsor
    Assistance Publique Hopitaux De Marseille
Updated on 19 February 2024
shock
vasopressor
oliguria
systolic blood pressure
hypoperfusion
heart failure
acute heart failure
hyperlactatemia
pulmonary edema
confusion

Summary

Cardiogenic shock (CC) is one of the major challenges of current cardiology. Despite the difficulty of establishing a strict and consensual definition, it is accepted that the CC clinically corresponds to persistent hypotension (systolic blood pressure 90 mmHg for at least 30 minutes or need for vasopressor support) associated with signs of visceral hypoperfusion (confusion, mottling, oliguria, hyperlactatemia), and hemodynamic with a lowered heart index ( 1.8 L/min/m2) despite appropriate or high filling pressures. This definition of the European Society of Cardiology (ESC) masks however the great variability of hemodynamic tables grouped under the term of CC and severity levels, also variable.However, it was suggested that the etiology of CC influenced both its hemodynamic profile and therefore its therapeutic management but also its prognosis in the medium and long term.

Description

CC diagnosis remains difficult to carry on admission and is sometimes delayed. Therefore, we would like to compare hemodynamic data from patients with CC status to those admitted for acute heart failure (ICA) to determine if a hemodynamic variable at entry would facilitate the diagnosis of CC.

Details
Condition Cardiogenic shock
Age 18years - 100years
Clinical Study IdentifierNCT04467294
SponsorAssistance Publique Hopitaux De Marseille
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

Patients in Cardiac Shock
mmHg hypotension or requiring inotropic or vasopressor support
owered cardiac output ( 1.8 L/min/m2) to trans-thoracic cardiac ultrasound with high or normal filling pressures
peripheral hypoperfusion. patients admitted for acute heart failure (ICA) (Acute pulmonary edema chart or left congestive heart failure without CC sign and with ultrasound FEVG at entry 40%.)

Exclusion Criteria

Pregnant or nursing women
Age 18 years
Person of full age under guardianship
Staying in a health or social facility
Person not covered by a social security scheme
Person deprived of liberty
Shocks from other etiologies
Patient with initial cardiac arrest
Patient with cardiogenic shock due to right ventricular dysfunction
Patient with pulmonary embolism
Patient with tamponade
Refusal to participate
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