Probe-based Confocal Laser Endomicroscopy in Critically Ill COVID-19 Patients

  • STATUS
    Recruiting
  • participants needed
    15
  • sponsor
    Federal Research Clinical Center of Federal Medical & Biological Agency, Russia
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Updated on 19 February 2024
See if I qualify
critical illness
ct scan
pneumonia
chronic obstructive pulmonary disease
covid-19
critically ill
respiratory failure
lung disease

Summary

The study is devoted to the comparative analysis of the data received in patients with COVID-19 lung pathology using the method of probe-based confocal laser endomicroscopy of distal airways and two reference methods: high resolution computed tomography and morphology (in some patients).

Details
Condition Covid 19
Age 18years - 90years
Treatment miniprobe Alveoflex
Clinical Study IdentifierNCT04451889
SponsorFederal Research Clinical Center of Federal Medical & Biological Agency, Russia
Last Modified on19 February 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

Patient Informed Consent
the diagnosis of COVID-19 or one of the following lung diseases: chronic obstructive pulmonary disease, pneumonia, solitary nodule, pulmonary sarcoidosis, idiopathic interstitial pneumonia, hypersensitivity pneumonitis, pulmonary vasculitis, pulmonary eosinophilia, hemochromatosis, histiocytosis X, pulmonary lymphangioleiomyomatosis; alveolar proteinosis, other rare lung disease
high resolution computed tomography scans performed not later than one month before pCLE (for non-COVID-19)
planned or performed histology (for non-COVID-19)
Severe respiratory failure

Exclusion Criteria

pregnancy or breast feeding
lung bleeding
any acute or chronic disease that may be a contraindication to bronchoscopy
any diseases of hematopoietic system
taking part in other clinical trials
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