Lung Irradiation for COVID-19 Pneumonia

  • STATUS
    Recruiting
  • participants needed
    48
  • sponsor
    Brigham and Women's Hospital
Updated on 19 February 2024
cancer
corticosteroids
aspirin
antiviral drugs
pneumonia
oximetry
azithromycin
chloroquine
SARS
ritonavir
hydroxychloroquine
oseltamivir
coronavirus infection
lopinavir
lopinavir/ritonavir
remdesivir
favipiravir
low dose radiation therapy
azithormycin
acute respiratory syndrome (sars)

Summary

In this research study the investigators want to learn more about the potential benefit of radiation to the lung to improve the health of patients who are hospitalized with Coronavirus-19 (COVID-19) due to infection with a virus called SARS-CoV-2. This infection causes inflammation of the lung, which can make it difficult to breathe. As a result, patients may need supplemental oxygen or be placed on a ventilator. The investigators believe that low dose radiation therapy to the lung may reduce this inflammation and increase the likelihood that patients will need less oxygen support such as ventilation or supplemental oxygen, or be discharged from the hospital in fewer days, compared to without radiation therapy. The amount of radiation is much lower than what is typically used to treat other conditions such as cancer, although it is higher than the dose used for routine medical imaging.

Details
Condition SARS-CoV 2
Age 40-100 years
Treatment Phase 1, Phase 2
Clinical Study IdentifierNCT04393948
SponsorBrigham and Women's Hospital
Last Modified on19 February 2024

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