Efficacy of Subcutaneous Ivermectin With or Without Zinc and Nigella Sativa in COVID-19 Patients

  • STATUS
    Recruiting
  • participants needed
    40
  • sponsor
    Sohaib Ashraf
Updated on 19 February 2024
covid-19
zinc
SARS
ivermectin
acute respiratory syndrome (sars)
nigella sativa / black cumin

Summary

To measure the effect of Ivermectin (sub-cutaneous) with or without zinc and Nigella sativa in treating the COVID-19 patients to clear viral load of SARS-CoV-2 along with reduction in severity of symptoms and length of hospitalization of patients with COVID-19.

Description

This is a parallel assigned, randomized, controlled, multi-armed, investigator Initiated interventional study is designed to demonstrate efficacy to lower the viral load of COVID-19 and to demostrate the antiviral effects of subcutaneous Ivermection with or without zinc and Nigella sativa. in mild to moderate symptomatic patients who consent to randomization following a new diagnosis in Pakistan with COVID-19 (PCR positive). Investigators will follow up with participants daily and PCR will be done on alternate days in BSL-3 lab. Dose will only be repeated if test remained positive..

Details
Condition Coronavirus Infection, COVID, Sars-CoV2
Age 18-100 years
Treatment Placebo, zinc, Nigella Sativa / Black Cumin, Ivermectin Injectable Solution
Clinical Study IdentifierNCT04472585
SponsorSohaib Ashraf
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

Nasopharyngeal RT-PCR positive SARS-CoV-2 patient with mild to moderate disease
Age 18 and above
BMI 18-28 kg/m

Exclusion Criteria

Allergy to any drug
Co-morbidities: any pre-existing cardiac disease, pulmonary disease
Arrhythmias
Pregnancy
RT-PCR performed >3 days prior to enrollment
Clear my responses

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