Hemodynamic Changes Due to Prone Position

  • STATUS
    Recruiting
  • participants needed
    10
  • sponsor
    University Hospital Hradec Kralove
Updated on 19 February 2024
hemodynamic instability

Summary

Perioperative prone position may be associated with hemodynamic instability. The causes of instability have not yet been precisely elucidated. The aim of this study is to demonstrate physiological changes during prone positioning in healthy volunteers .

Description

The prone position could decrease the cardiac index (CI), mainly due to reduction in stroke volume, with little changes in heart rate. Mean arterial pressure (MAP) could be maintained by increased systemic vascular resistance (SVR) in the majority of patients.

The aim of this study is to describe hemodynamic changes in two different surgical prone positions in 10 healthy non-anesthetized volunteers (flat position and using a support system allowing a free abdomen) by non-invasive measurement of hemodynamics (ClearSight, Edwards) and indirectly evaluated intra-abdominal pressure using ultrasound. The ClearSight system provides advanced hemodynamic parameters (cardiac index CI, stroke volume SV, stroke volume variation SVV, systemic vascular resistance SVR, mean arterial pressure MAP) from a finger cuff.

Details
Condition Prone Position, Hemodynamics Instability
Age 18-100 years
Treatment Prone position
Clinical Study IdentifierNCT04491331
SponsorUniversity Hospital Hradec Kralove
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

age >18 years, American Society of Anesthesiologists (ASA) Physical Status Classification I-II, agreement with study participation

Exclusion Criteria

disagreement with study participation, BMI over 40
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