Hyperlactatemia During and After Tumorcraniotomy
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- STATUS
- Recruiting
-
- participants needed
- 450
-
- sponsor
- Rigshospitalet, Denmark
Summary
This study aims to investigate the association between hyperlactatemia and neurological disability, length-of-stay and mortality in patients who undergo tumorcraniotomy. The risk factors that induce lactat accumulation will also be explored.
Description
Hyperlactatemia is a frequent occurrence in brain tumor surgery. The existing studies, however, are all retrospective, reporting varying effects on clinical outcome. One study reported new neurological deficitis, some found an association with extended hospital stay, while others found no association with outcome. It is therefore important to conduct a prospective study of hyperlactatemia in this patientgroup.
Participants in this study will follow the standard treatment protocol for tumorcraniotomy, aside from 2-3 additional, perioperative blodgas analyses and 2 standardized measurements of neurological disability.
Details
| Condition | Surgery, Metabolic disorder, Surgical aspects, Surgery, Malignant neoplasm of brain, Anesthesia, Anesthesia |
|---|---|
| Age | 18years - 100years |
| Treatment | Serum-lactate < 2,2 mmol/L, Serum-lactate >/= 2,2 mmol/L |
| Clinical Study Identifier | NCT04410315 |
| Sponsor | Rigshospitalet, Denmark |
| Last Modified on | 19 February 2024 |
How to participate?
Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
Learn moreIf you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
Learn moreComplete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.
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