Impact of Sinus Surgery on Individuals With Cystic Fibrosis

  • STATUS
    Recruiting
  • participants needed
    170
  • sponsor
    University of Colorado, Denver
Updated on 19 February 2024
fibrosis
medical therapy
genetic testing
cystic fibrosis
sinusitis
rhinosinusitis
sweat chloride test
sinus surgery
sweat chloride
sweat test

Summary

This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS). Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analyzed will include pulmonary, quality of life, and others.

Details
Condition Pulmonary Disease, Cystic Fibrosis, Cystic Fibrosis, Pancreatic disorder, Chronic Rhinosinusitis (Diagnosis)
Age 18-99 years
Clinical Study IdentifierNCT04469439
SponsorUniversity of Colorado, Denver
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

Subjects between the ages of 18 years old (inclusive) and 99 years old (inclusive, subjects over the age of 89 will be recorded to be 89 years old)
Diagnosed with cystic fibrosis as established by genetic testing combined with clinical assessment and/or sweat chloride
Diagnosed with chronic rhinosinusitis by multidisciplinary sinusitis guidelines
chronic rhinosinusitis symptoms persisting beyond initial medical treatment
Counseled for endoscopic sinus surgery and ongoing medical therapy with each patient electing their preferred treatment

Exclusion Criteria

Underwent endoscopic sinus surgery in past 12 months
Will obtain follow up care at non-participating institutions
Unable to complete follow-up surveys
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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