Manchester Lung Health Study

  • STATUS
    Recruiting
  • participants needed
    9730
  • sponsor
    Manchester University NHS Foundation Trust
Updated on 19 February 2024
cancer
ct scan
lung cancer
lung cancer screening
low-dose chest computed tomography
ct scan chest
cancer screening
chest ct

Summary

The Manchester Lung Health Study (qUEST) will assess the uptake of a community-based lung cancer screening service and its impact across a deprived area of North and East Manchester, which has high rates of lung cancer. One measure will be to compare the number and stage of lung cancers detected through screening to those detected outside of screening. In addition we will investigate the potential of a blood and nose test to detect lung cancer or to help decide who would benefit from screening. We will also see if these samples can help with the interpretation of CT scans. One of the problems with lung cancer CT screening is that you detect lung nodules in which we are not sure if they are benign or cancerous. Therefore we are also looking to see if a biomarker can help us work out which are cancerous and which are benign.

Details
Condition Pulmonary Disease, Lung Neoplasm, lung cancer, lung cancer
Age 55years - 80years
Treatment Lung Cancer Screening, Biomarkers
Clinical Study IdentifierNCT04409444
SponsorManchester University NHS Foundation Trust
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

Any individual attending the M-LHC service who is eligible and agrees to undergo LDCT screening
Has consented to the main study

Exclusion Criteria

Unable to give informed consent to study participation
Decline participation in LDCT lung cancer screening
Known blood borne virus e.g. HIV or Hepatitis B, C
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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