Neoadjuvant Chemotherapy With or Without Metformin in Early Breast Cancer.
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- STATUS
- Recruiting
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- participants needed
- 120
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- sponsor
- Mansoura University
Summary
Metformin is a widely used anti-diabetic drug. Several studies have pointed out a potentially beneficial effect of metformin therapy in diabetic cancer patients. Several studies are investigating the anti-tumor effect of metformin in early breast cancer. However, the enhancing effect of metformin on anti-tumor immunity has only been demonstrated in animal models. This study examines the immune effect of metformin in breast cancer patients treated with preoperative chemotherapy.
Details
| Condition | Breast Cancer, Breast Cancer |
|---|---|
| Age | 18-65 years |
| Treatment | Placebo Oral Tablet, Metformin |
| Clinical Study Identifier | NCT04387630 |
| Sponsor | Mansoura University |
| Last Modified on | 19 February 2024 |
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