Dual-scopic Pancreatic Necrosectomy (DPN)

  • STATUS
    Recruiting
  • End date
    Dec 31, 2025
  • participants needed
    20
  • sponsor
    First People's Hospital of Hangzhou
Updated on 19 February 2024
ct scan
cavity
abdominal pain
cavities
lipase
serum amylase
abdominal ct scan
cholecystectomy
colic
necrosectomy
stomach pain
normal saline
seldinger technique

Summary

The LPN procedure is performed under general anesthesia. The transperitoneal access to peripancreatic space is via the gastro-colic ligament and greater omentum, effusion and pus is removed by laparoscopic forceps and suction. Laparoscopic cholecystectomy (LC) is performed during the LPN procedure on patients with indication.

The NPN procedure is followed by the standard retroperitoneal approach. After the catheter is exchanged over a guide wire and serially dilated up from 6F to 24F followed by Seldinger technique, the access track to the necrotic cavity is established. A nephroscope is inserted into the cavity through the track for debridement. Using forceps and suction, the peripancreatic solid necrotic tissue and pus is grasped and removed. A large-bore irrigating drain is left in the cavity, with continuous irrigation by warm normal saline solution at a rate of 100-125 ml/h after surgery.

Details
Condition Pancreatitis, Pancreatitis, Pancreatic disorder, Necrotizing pancreatitis
Age 18-100 years
Treatment Dual-scopic pancreatic necrosectomy(DPN)
Clinical Study IdentifierNCT04443595
SponsorFirst People's Hospital of Hangzhou
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

All patients ages 18 or above admitted to UPMC with a diagnosis of AP based on at least 2 of the following criteria:(i) abdominal pain characteristic of AP (ii) serum amylase and/or lipase 3 times the upper limit of normal (iii) characteristic findings of AP on abdominal CT scan will be screened for study enrollment

Exclusion Criteria

Less than 18 years of age
Pregnant women
Presence of renal dysfunction (Cr>1.5mg/dL)
Pre existing heart dysfunction or NYHA classification score above III
Coagulation disorder
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.