Thyroid Disease Diagnosis by Mutiple Ultrasonic Factors.

STATUS

Recruiting
participants needed

300
sponsor

National Taiwan University Hospital

Updated on 19 February 2024

See if I qualify

Summary

Show definitions

4 to 7 percent of adult population has a palpable thyroid nodule and 17% to 27% of cases can be found when examined by sonography. Although the incidence of the thyroid nodules is high, only 1 of 20 clinically identified nodules is malignant.

Several gray scale sonographic characteristics have been suggestive of malignancy, including hypoechoigenicity, micro calcification, blurred margin and intranodular vascularity. The intranodular vascularity has been studied in several researches. But the previous studies usually evaluated the vascularity by color Doppler sonography and only divided into several categories subjectively. And the result is controversial.

The evaluation of the tumor microcirculation by Doppler ultrasound has been used in many tumors and defined as vascularity index (VI). The power Doppler sonography has many advantages over color Doppler ultrasound in studying the vascularity. It is more sensitive, less noisy. Power Doppler can detect the blood flow of small internal tumor vessels with a diameter of less than 100m at slow flow rates on the order of a few mm per second1,2 According to our previous study, the vascularity index(PDVI) of thyroid tumor by power Doppler ultrasound between benign and malignant one are statistically different.

In the present study, we examine different PDVI of thyroid tumors and the traditionalB-modeultrasound features including the heterogeneity, echogenicity, margin status, and the presence of microcalcification. We consider the several factors simultaneously by statistical model (PCA, FLD). In the outpatient clinic based population setting, we want to reappraise the accuracy of the new model of multi-factorial ultrasound diagnosis with the conventional fine-needle aspiration cytology.

Details

Condition	Thyroid Disease Diagnosis by Mutiple Ultrasonic Factors
Age	100years or below
Clinical Study Identifier	NCT04388956
Sponsor	National Taiwan University Hospital
Last Modified on	19 February 2024

How understandable was the trial content above?

Hard to understand

Easy to understand

Eligibility		Yes	No	Not Sure
Inclusion Criteria
	We plan to recruit 300 patients who have discrete solid thyroid tumors need to
	undergo fine-needle aspiration cytology to provide the tentative diagnosis
	The inclusion criteria were discrete thyroid tumors with mainly solid content
	(>50% solid content) and diameter of tumors between 0.5-3cm. The exclusion
	criteria were abnormal thyroid function, past history of thyroiditis
	multinodular goiter, and cystic tumors

How to participate?

Step 1 Connect with a study center

Send a message

Enter your contact details to connect with study team

First name*

Last name*

Email*

Phone number*

Other language

I am at least 18 years old.

By sending a message, I agree to share my information with the study team for the selected site and consent to receive emails and text messages for trial updates, notifications, and related communication. TrialX values your privacy; your information will be handled in accordance with our Privacy Policy

Step 2 Get screened

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

Step 3 Enroll in the clinical study

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Step 4 Get your study results

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Thyroid Disease Diagnosis by Mutiple Ultrasonic Factors.

Summary

Details

How to participate?

Similar trials to consider

Not finding what you're looking for?

Study AnnotationsStudy Notes

Add a private note

Study Definition

Add a private note

Thyroid Disease Diagnosis by Mutiple Ultrasonic Factors.

Summary

Details

How to participate?

Similar trials to consider

Not finding what you're looking for?

Sign up as a volunteer to stay informed

Study AnnotationsStudy Notes

Add a private note

Study Definition

Add a private note