Epileptic Activity in Patients With Alzheimer's Disease and Lewy Body Dementia

  • STATUS
    Recruiting
  • participants needed
    120
  • sponsor
    Danish Dementia Research Centre
Updated on 19 February 2024
depressive symptoms
psychiatric disorder
selective serotonin reuptake inhibitors
functional magnetic resonance imaging
depression
mental disorders
functional mri
alzheimer's disease
mini-mental state examination
ssri
cerebral blood flow
epilepsy
dementia
drugs of abuse
neuropsychological test
neuropsychological assessment
lewy body dementia
lewy body disease
mild depression
illegal drugs

Summary

In the current study, the investigators will examine the extent of subclinical epileptic activity in patients with Alzheimer's disease and patients with Lewy body dementia as compared to healthy elderly controls. The participants will wear a new device called "ear-EEG", which makes it possible to record EEG for longer periods of time while at home. Furthermore, the investigators want to investigate whether there is an association between subclinical epileptic activity and the cerebral blood flow as measured with functional MRI.

Details
Condition Lewy Body Disease, Epilepsy, Epilepsy, Dementia, Dementia, Alzheimer's Disease, Alzheimer's Disease
Age 50years - 90years
Clinical Study IdentifierNCT04436341
SponsorDanish Dementia Research Centre
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

Normal cognition as evaluated at the clinical examination
The participant is a native Danish speaker
The participant has at least attended school for 7 years
The participants' hearing and vision is sufficient to participate in neuropsychological tests
The participants' general condition of health allows that the participant can cooperate with the trial
The participant does not suffer from psychiatric diseases (except mild depressive symptoms or mild depression) or neurological diseases that affect the brain
The participant does not have any contraindications for MRI or MRI contrast

Exclusion Criteria

The participants is suffering from uncontrollable movements of the face as for example oral dyskinesia
The participant is suffering from epilepsy or receives anti-epileptic medication
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