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Testing the Safety of CB-5339 in Patients With Cancer

Studying CB-5339's safety in cancer patients.

Recruiting
18 years and older
All
Phase 1

Study Purpose: This research is exploring the safety and best dosage of an investigational medication for adults with advanced solid tumors or lymphomas. It aims to see if the medication can stop cancer cell growth by blocking certain enzymes.

Duration & Visits: Participants will take the medication by mouth for 4 days, then have 3 days off in each 28-day cycle. The study continues as long as the treatment is effective and without severe side effects. After finishing, there’s a 30-day follow-up.

Eligibility: Adults with advanced cancer that has spread and who have tried standard treatments without success. Participants need to be healthy enough to join and willing to use birth control during the study.

  • Commitment: The study involves regular cycles of medication and follow-ups.
  • Considerations: Participants must not have certain health issues like uncontrolled infections or recent heart problems.
  • Requirements: Participants need to agree to two biopsy procedures if possible and avoid other investigational treatments.

Contact us to see if you qualify and want to participate in this study.

Study details
    Metastatic Malignant Solid Neoplasm
    Aggressive Non-Hodgkin Lymphoma
    Indolent Non-Hodgkin Lymphoma
    Locally Advanced Malignant Solid Neoplasm

NCT04372641

National Cancer Institute (NCI)

19 February 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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