LRRK2 G2385R Leucocyte and Urine Biomarker Study

  • STATUS
    Recruiting
  • participants needed
    150
  • sponsor
    University of Malaya
Updated on 19 February 2024
parkinson's disease
movement disorder

Summary

Given the emerging evidence on LRRK2-related biomarkers, this project will focus on identifying leucocyte and urine biomarkers that are altered by the LRRK2 G2385R variant, and investigating the effects of LRRK2 kinase inhibitor (MLi-2) on these biomarkers, using immunoblotting and mass spectrometry.

Details
Condition Parkinson's Disease, Parkinson's Disease
Age 18years - 100years
Treatment This is a non-interventional study
Clinical Study IdentifierNCT04436848
SponsorUniversity of Malaya
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

Diagnosis of Parkinson's disease assigned by a movement disorder specialist according to clinical diagnostic criteria
Age above 18 year-old
Provision of a written informed consent

Exclusion Criteria

Physical or mental incapacity to complete study protocol
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