A Study to Evaluate the Safety Pharmacokinetics and Activity of GDC-6036 in Patients With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation
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- STATUS
- Recruiting
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- participants needed
- 108
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- sponsor
- Genentech, Inc.
Summary
This is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or metastatic solid tumors with a KRAS G12C mutation.
Details
| Condition | Non-Small Cell Lung Cancer, Non-Small Cell Lung Cancer, Colorectal Cancer, Colorectal Cancer, Rectal disorder, Advanced Solid Tumors |
|---|---|
| Age | 18years - 100years |
| Treatment | GDC-6036 |
| Clinical Study Identifier | NCT04449874 |
| Sponsor | Genentech, Inc. |
| Last Modified on | 19 February 2024 |
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