Hypofractionation And Ultra-Hypofractionation In Adjuvant Radiotherapy For Breast Cancer
-
- STATUS
- Recruiting
-
- participants needed
- 100
-
- sponsor
- Alexandria University
Summary
Prospective randomized study comparing 5 fractions in alternative days to standard 15
fractions regarding effectiveness and feasibility during
Description
In Alexandria, the number of working linear machines are limited with overcrowded waiting
list which lead to prolongation of overall treatment time and delay in starting
The rationale behind
This study will include at least 100 patients with non metastatic histologically proved
The patients will be randomized into two
- Control
arm : will include 50 patients who will receive standard 40.05 Gray (2.67 Gy/fx) over 15 fractions with or without boost over 3 weeks biologically effective dose (BED) for early andlate effect equal 50.74.Gy10 and 75.69 Gy3 respectively. - Experimental
arm : will include 50 patients who will receive 26 Gray (5.2 Gy/fx) over 5 fractions over 1.5 weeks with BED for early andlate effect equal 39.52 Gy10 and 71.07 Gy3 respectively
Details
| Condition |
|
|---|---|
| Age | 50years - 100years |
| Treatment |
|
| Clinical Study Identifier | NCT04434677 |
| Sponsor | Alexandria University |
| Last Modified on | 19 February 2024 |
How to participate?
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Learn moreComplete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.
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