Blood Pressure Management on Cardiovascular AdveRse Events After Major Abdominal Surgery
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- STATUS
- Recruiting
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- End date
- Jun 5, 2025
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- participants needed
- 1500
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- sponsor
- Nanfang Hospital of Southern Medical University
Summary
This study is a multicenter randomized controlled trial comparing an intensive intraoperative blood pressure management strategy versus conventional practice for preventing cardiovascular events in high-risk patients undergoing major abdominal surgery.
Description
Intraoperative hypotension has been associated with cardiovascular events after non-cardiac surgery. However, whether avoiding intraoperative hypotension can reduce the incidence of postoperative cardiovascular events remains unclear. The objective of this study is to assess the effects of an intensive intraoperative blood pressure management strategy (to maintain intraoperative MAP 80mmHg) with that of conventional practice (to maintain intraoperative MAP 65mmHg) on the incidence of cardiovascular events after major abdominal surgery.
Details
| Condition | Cardiovascular Complication |
|---|---|
| Age | 45-100 years |
| Treatment | Intensive intraoperative blood pressure management, Conventional intraoperative blood pressure management |
| Clinical Study Identifier | NCT04430920 |
| Sponsor | Nanfang Hospital of Southern Medical University |
| Last Modified on | 19 February 2024 |
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