Study Purpose: This research aims to find out the side effects of using bone marrow-derived stem cells to treat painful low back conditions called lumbar facet joint arthropathies.
What to Expect: Participants will receive an injection of investigational medication into their back and be monitored over a two-year period. This involves several check-ups, including one on the day of the injection, and follow-ups at 1 day, 3-5 days, 2 weeks, and then at 3, 6, 12, 18, and 24 months after treatment.
- The study lasts for 24 months with multiple visits.
- Participants must be between 40-70 years old with specific low back pain.
- Participants should not be extremely obese or pregnant, and must not have certain back conditions or recent procedures.
Eligibility: Interested individuals should have a specific type of back pain (L3-S1 facet joint arthropathy) confirmed by a test called medial branch block. They must be able to understand the study and agree to follow all procedures, including tests and visits. This study is open to individuals who are not pregnant, extremely obese, or have certain medical conditions.