Study Purpose: This study aims to find out if an investigational medication is safe for people with liver disease caused by drinking too much alcohol. Participants should have stopped drinking for at least 2 weeks but no more than 6 months before starting the study.
- Who Can Join: Adults aged 21 and up with alcohol-related liver disease and alcohol use disorder (AUD).
- Time Commitment: Participants will be involved in a pilot safety assessment with different phases based on the severity of their liver condition.
- Eligibility Considerations: Participants must not have severe kidney issues, serious heart problems, or be pregnant. They should be able to give consent themselves.
**Key Terms Explained:**
- Liver Disease: A condition where the liver is damaged, often due to excessive alcohol consumption.
- Alcohol Use Disorder (AUD): A medical condition where a person has difficulty controlling alcohol use.
- MELD-Na Score: A number that helps assess the severity of liver disease.
- Glomerular Filtration Rate (GFR): A measure of how well kidneys are working.
- Congestive Heart Failure: A condition where the heart doesn't pump blood as well as it should.
- Hypotension: Low blood pressure that might need medication.
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