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Daily Long-Term Intermittent Fasting for the Prevention of PSA-Recurrence in Patients With Localized Prostate Cancer After Radical Prostatectomy

Trying intermittent fasting to prevent prostate cancer recurrence after surgery.

Not Recruiting
18 years and older
Male
Phase N/A

This research is looking at whether daily, long-term intermittent fasting can help prevent a rise in PSA levels in men who have been treated for prostate cancer. PSA is a protein made by the prostate, and high levels might mean the cancer is coming back. The study involves eating during an 8-hour window each day (like 1 PM to 9 PM) and fasting the other 16 hours. This routine lasts up to 1 year or until other treatments are needed.

Key Points:

  • The study lasts for up to 1 year.
  • Participants need to follow the daily fasting schedule.
  • Men should have had prostate surgery and a PSA level of 0.1 ng/mL or higher within 24 months of surgery.

Men who want to join should have had surgery for localized prostate cancer, not received certain treatments before surgery (like hormone therapy), and must be able to fast. This study is not suitable for those with diabetes or on hormone therapy.

Study details
    Stage I Prostate Cancer AJCC v8
    Stage II Prostate Cancer AJCC v8
    Stage IIA Prostate Cancer AJCC v8
    Stage IIB Prostate Cancer AJCC v8
    Stage IIC Prostate Cancer AJCC v8
    Stage III Prostate Cancer AJCC v8
    Stage IIIA Prostate Cancer AJCC v8
    Stage IIIB Prostate Cancer AJCC v8
    Stage IIIC Prostate Cancer AJCC v8

NCT04288336

Mayo Clinic

19 February 2024

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