Botulinum Toxin Injection in the Treatment of Open Abdomen

  • STATUS
    Recruiting
  • participants needed
    30
  • sponsor
    University of Oulu
Updated on 19 February 2024
botulinum toxin
injection of botulinum toxin

Summary

Botulinum toxin has been widely approved and utilized in the treatment of complex abdominal wall hernias. Botulinum toxin has been only randomly studied in the treatment of open abdomen.

Description

30 consecutive patients who have open abdomen for any indication, will have 300 IU botulinum toxin injected in three spots in either sides of the abdomen within 72 hours of the start of open abdomen. The hypothesis is botulinum toxin relaxes abdominal wall musculature to ensure better and faster closure of the open abdomen.

Details
Condition Open Abdomen, Botulinum Toxin Injection
Age 18-100 years
Treatment Botulinum Toxins
Clinical Study IdentifierNCT04283916
SponsorUniversity of Oulu
Last Modified on19 February 2024

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