Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas

  • STATUS
    Recruiting
  • End date
    Feb 28, 2027
  • participants needed
    1174
  • sponsor
    H. Lee Moffitt Cancer Center and Research Institute
Updated on 19 February 2024
cancer
endoscopy
cyst
pancreatitis
intraductal papillary mucinous neoplasms of the pancreas
ipmn

Summary

The Florida Pancreas Collaborative wants to partner with individuals who are known to have, or are suspected to have a pancreatic lesion, tumor, cyst, mass, cancer, or pancreatitis and are undergoing diagnosis and treatment at a participating institution. The goals of this project are to build a large database of information obtained from blood, tissue, medical images, surveys and information from routine care to develop noninvasive diagnostic approaches that could be used as decision-making tools to effectively personalize clinical care.

Details
Condition Pancreatic Cancer, Pancreatic Cancer, Pancreatic disorder, Pancreatic Cyst, Neoplasm of unspecified nature of digestive system
Age 18-100 years
Treatment data collection, Blood Sample collection, Tissue sample collection
Clinical Study IdentifierNCT04275557
SponsorH. Lee Moffitt Cancer Center and Research Institute
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

Individuals who present to the GI clinic, surgery, or endoscopy at Moffitt, UF, or UM with a clinical suspicion for (or diagnosis of) a pancreatic lesion, cyst, mass, cancer, or pancreatitis based on symptoms, imaging, or blood-work and has not had any treatment involving their pancreas
Able to understand and voluntarily sign the informed consent
Willing to complete study questionnaire(s) and donate medical images and biological specimens (including blood, cystic fluid, and tissue) obtained at the time of standard of care procedures (biopsy, surgery, and venipuncture) after signing the informed consent document

Exclusion Criteria

No suspicion or diagnosis of a pancreatic lesion, cyst, mass, cancer, or pancreatitis
Has a diagnosis of a pancreatic lesion, cyst, mass, cancer, or pancreatitis and has already undergone treatment involving the pancreas (which may involve surgery, chemoor immuno-therapy, and/or radiation)
Unable to provide informed consent
Unwilling to complete study questionnaire(s) and/or donate biological specimens or images
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How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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