Mechanism of Action of Transcranial Magnetic Stimulation
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- STATUS
- Recruiting
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- participants needed
- 54
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- sponsor
- Massachusetts General Hospital
Summary
This is an observational neuroimaging study assessing the effects of TMS on the brains of patients with unipolar depression.
Description
This project aims to use functional connectivity magnetic resonance imaging (fcMRI) to study patients with unipolar depression receiving TMS. Patients will be scanned before and after a full course of TMS and clinical measures for depression severity and memory will be obtained at the same times.The project has the following aims and hypothesis: (1) to determine the therapeutic antidepressant mechanism of action of TMS at the circuit level (2) to study the use of fcMRI as a state biomarker for depression (3) to study the use of fcMRI as a predictor of response for depression.
Details
| Condition | Major depression, Endogenous depression, Depression, Depression |
|---|---|
| Age | 18years - 80years |
| Treatment | Transcranial magnetic stimulation |
| Clinical Study Identifier | NCT04278521 |
| Sponsor | Massachusetts General Hospital |
| Last Modified on | 19 February 2024 |
How to participate?
Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
Learn moreIf you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
Learn moreComplete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.
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