Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus
-
- STATUS
- Not Recruiting
-
- End date
- Dec 28, 2025
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- participants needed
- 12
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- sponsor
- Mayo Clinic
Summary
To investigate the potential efficacy of dupilumab in the treatment of moderate to severe chronic hepatic pruritus.
Description
This is a 22-week (2 week screening, 18-week treatment period followed by a 2 week followup), phase II, open label, exploratory study to investigate the potential efficacy of FDA approved dupilumab in the treatment of adults with moderate to severe chronic hepatic pruritus. Subjects will be screened at outpatient clinic visit appointments and interested qualified subjects will be consented and offered participation in this trial. Once consent has been obtained, baseline values will be established and subjects will begin treatment and follow-up for the next 20 weeks. A final visit will be needed for evaluation and questionnaire completion.
Details
| Condition | Pruritus, Dermatosis |
|---|---|
| Age | 18years - 100years |
| Treatment | Dupilumab 300Mg Solution for Injection |
| Clinical Study Identifier | NCT04256759 |
| Sponsor | Mayo Clinic |
| Last Modified on | 19 February 2024 |
How to participate?
Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
Learn moreIf you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
Learn moreComplete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.
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