Primary Cyto-reductive Surgery Vs Neo-adjuvant Chemotherapy (NAC) in Epithelial Ovarian Cancer

  • STATUS
    Recruiting
  • participants needed
    80
  • sponsor
    Assiut University
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Updated on 19 February 2024
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cancer
ovarian cancer
epithelial ovarian cancer
adjuvant

Summary

Assessment of efficacy of primary cyto-reductive surgery in patients with advanced primary epithelial ovarian cancer in Comparison to patients receiving neo-adjuvant chemotherapy (NAC) followed by surgery in complete excision of the tumor reaching R0 without significant morbidity.

Details
Condition Advanced Cancer
Age 18years - 80years
Treatment 1ry cyto-reductive surgery, Neoadjuvant chemotherapy followed by surgery
Clinical Study IdentifierNCT04257786
SponsorAssiut University
Last Modified on19 February 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

Female patients diagnosed with epithelial ovarian cancer (By histopathology)
Age 18 years old
Advanced defined as (stage 2D or more ) by surgical staging
Performance status (PS) according to Eastern Cooperative Oncology Group (ECOG)
Chemotherapy nave
Informed consent

Exclusion Criteria

Patients previously received chemotherapy or radiotherapy to any part of the
abdomen or pelvis
Patients with uncontrolled infection
Patients with active bleeding or conditions associated with high risk of
bleeding
contraindications for surgery
contraindications To chemotherapy - bevacizumab
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