Characterization of Methylation Patterns in Cancer and Non-Cancer cfDNA
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- STATUS
- Recruiting
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- End date
- Dec 28, 2026
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- participants needed
- 6000
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- sponsor
- Nucleix Ltd.
Summary
Nucleix EpiCheck tests analyzes the methylation pattern in a panel of DNA methylation biomarkers and determines whether this pattern is consistent with cancer under test or with non-cancer tissue.
This study is being performed as part of the development process of the Pan Cancer EpiCheck test which includes the identification of different methylation profiles in various cancer types and healthy controls.
Description
The aim of this study is to characterize methylation patterns that will distinguish cancer from normal samples and will be able to recognize the origin of the cancer by collecting cfDNA (circulating free DNA) from blood samples collected from patients with a new diagnosis of cancer and from healthy volunteers who do not have diagnosis or history of cancer. Identifying those methylation patterns may assist in the development of blood test that will be able to detect the presence and the origin of wide range of human cancers
Details
| Condition | Hematologic Malignancy, Blood disorder, Cancer, Solid Tumor |
|---|---|
| Age | 22-80 years |
| Treatment | Blood collection |
| Clinical Study Identifier | NCT04264767 |
| Sponsor | Nucleix Ltd. |
| Last Modified on | 19 February 2024 |
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
Learn moreIf you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
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