A Trial of ZL-1201 in Subjects With Advanced Cancer
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- STATUS
- Recruiting
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- participants needed
- 65
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- sponsor
- Zai Lab (Shanghai) Co., Ltd.
Summary
First in Human, Phase I Trial of Anti-CD47 Antibody ZL-1201 in Subjects with Advanced Cancer
Description
This is a first-in-human, dose escalation trial of an anti-CD47 antibody. The major aims of the study are to define the safety profile of this new drug, and to determine a recommended dose and schedule for potential additional trials. This study The study is composed of 3 stages: Part 1 low dose group, and Part 2 high dose group. Part 3 pharmacodynamic (PD)/ dose expansion cohort will open after the completion of Part 1 and 2.
Details
| Condition | Locally Advanced Solid Tumor |
|---|---|
| Age | 18-100 years |
| Treatment | ZL1201 |
| Clinical Study Identifier | NCT04257617 |
| Sponsor | Zai Lab (Shanghai) Co., Ltd. |
| Last Modified on | 19 February 2024 |
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
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