Cardiometabolic Health and Inflammatory Resolution

  • STATUS
    Recruiting
  • participants needed
    200
  • sponsor
    Göteborg University
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Updated on 19 February 2024
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Summary

The aim of this study is to determine how inflammatory resolution impacts cardiometabolic health and disease in subjects that are either lean (18.5-24.9 kg/m2), overweight (25.0-29.9 kg/m2) or obese (>30.0 kg/m2).

Details
Condition Voluntary Worker
Age 18years - 65years
Clinical Study IdentifierNCT04256330
SponsorGöteborg University
Last Modified on19 February 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

Informed signed consent has been obtained from the volunteer
The volunteer has a BMI greater than 18.5 kg/m2

Exclusion Criteria

The study staff contacting a potential participant perceives that the individual has difficulty understanding the information
An MD determines that the individual is on too many medications to participate
The individual takes a medication that is approved by the MD, but he/she is not willing or not able to wait with any potential morning medication until after their fasted blood-draw
The individual is younger than 18 years (relevant for the FAINT-1 and FAINT-2 cohorts)
The individual states that they have increased bleeding tendency or are using anti-coagulant (blood thinning) medication
The individual has some form of chronic inflammation
The individual regularly uses medication that affects inflammatory resolution (e.g., low-dose aspirin)
The individual uses immunosuppressive drugs (eg, methotrexate)
The individual regularly consumes fish oils (omega 3)
The individual has significant gastrointestinal problems
The individual smokes or uses chewing tobacco
The individual has been drinking alcohol two days before the study visit
The individual has tattoos or body piercings on the forearms and / or the stomach that can affect the examination
The individual does not follow instructions given in the research study
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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