Verification of Predictive Biomarkers for Pancreatic Cancer Treatment Using Multicenter Liquid Biopsy
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- STATUS
- Recruiting
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- End date
- Dec 31, 2025
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- participants needed
- 662
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- sponsor
- National Cancer Center, Korea
Summary
This study is for verification of predictive biomarkers for pancreatic cancer treatment using multi-center liquid biopsy.
Description
Clinical applicability of KRAS mutations using circulating-tumor DNA in pancreatic cancer patients.
- Quantification and monitoring of KRAS mutations Using droplet digital PCR in ctDNA extracted from collected patient samples.
- Correlation analysis of KRAS mutation results with clinical data.
Discovery of biomarkers for predicting pancreatic cancer prognosis through ctDNA panel.
- Gene panel composition for pancreatic cancer therapeutic target determination and monitoring.
- A panel was performed using gDNA and ctDNA of tumor tissue collected from pancreatic cancer patients.
- Comparative analysis of panel results and quantitative KRAS mutations and evaluation of clinical applicability.
Details
| Condition | Pancreas Adenocarcinoma |
|---|---|
| Age | 100years or below |
| Clinical Study Identifier | NCT04241367 |
| Sponsor | National Cancer Center, Korea |
| Last Modified on | 19 February 2024 |
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