Invasive Coronary Angiography Early in Ischemic Heart Failure

  • STATUS
    Recruiting
  • participants needed
    3000
  • sponsor
    Institute for Clinical Evaluative Sciences
Updated on 19 February 2024
heart disease
heart failure
angiography
myocardial infarction
acute heart failure
angina pectoris
troponin
angina

Summary

To compare the outcomes of patients with acute heart failure who undergo early coronary angiography vs. usual care

Details
Condition Acute Heart Failure
Age 18-100 years
Treatment Coronary angiography
Clinical Study IdentifierNCT04245605
SponsorInstitute for Clinical Evaluative Sciences
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

Adult patients with acute heart failure, hospitalized in
Ontario, Canada, with evidence of possible ischemic heart disease, defined as
at least one of: a) prior myocardial infarction, b) troponin elevation, or c)
angina

Exclusion Criteria

Recent myocardial infarction
Coronary angiogram or revascularization within previous 3 months before admission
Nonresidents of Ontario, invalid health card number
HF diagnosed after admission
Admission BNP or NT-proBNP not diagnostic of HF
Died within 14 days of admission
Palliative within 6 months prior to hospital admission
Elevated creatinine concentration
Documented anaphylactic contrast allergy
Ischemic or hemorrhagic stroke within 3 months prior to admission
Highest category of Hospital Frailty Risk Score
Active severe bleeding at time of hospital admission
Absolute platelet count < 20
Metastatic cancer
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