Survival Significance of Molecular Pathology and Genetic Variation in Brain Gliomas
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- STATUS
- Recruiting
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- End date
- Jun 1, 2025
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- participants needed
- 3000
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- sponsor
- The First Affiliated Hospital of Zhengzhou University
Summary
This study aims to collect clinical, radiological, pathological, molecular and genetic data including detailed clinical parameters, MR and histopathology images, molecular pathology and genetic data. This study seeks to find the prognostic and clinical significance based on molecular and genetic biomarkers/subgroups of gliomas.
Description
Precise classification based on molecular and genetic biomarkers/subgroups for gliomas is challenging. This study aims to collect clinical, radiological, pathological, molecular and genetic data including detailed clinical parameters, MR and histopathology images, molecular pathology (1p/19q co-deletion, MGMT methylation, IDH and TERTp mutations, etc) and genetic data (Whole exome sequencing, RNA sequencing, proteomics, etc). This study seeks to find the prognostic and clinical significance based on molecular and genetic biomarkers/subgroups of gliomas.
Details
| Condition | Mutation, Glioma, Molecular Sequence Variation |
|---|---|
| Age | 1years - 95years |
| Treatment | Glioma groups based on molecular pathology or genetic variation |
| Clinical Study Identifier | NCT04216537 |
| Sponsor | The First Affiliated Hospital of Zhengzhou University |
| Last Modified on | 19 February 2024 |
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