Survival Significance of Molecular Pathology and Genetic Variation in Brain Gliomas
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- STATUS
- Recruiting
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- days left to enroll
- 26
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- participants needed
- 3000
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- sponsor
- The First Affiliated Hospital of Zhengzhou University
Summary
This study aims to collect clinical, radiological, pathological, molecular and genetic data including detailed clinical parameters, MR and histopathology images, molecular pathology and genetic data. This study seeks to find the prognostic and clinical significance based on molecular and genetic biomarkers/subgroups of gliomas.
Description
Precise classification based on molecular and genetic biomarkers/subgroups for gliomas is challenging. This study aims to collect clinical, radiological, pathological, molecular and genetic data including detailed clinical parameters, MR and histopathology images, molecular pathology (1p/19q co-deletion, MGMT methylation, IDH and TERTp mutations, etc) and genetic data (Whole exome sequencing, RNA sequencing, proteomics, etc). This study seeks to find the prognostic and clinical significance based on molecular and genetic biomarkers/subgroups of gliomas.
Details
| Condition | Mutation, Glioma, Molecular Sequence Variation |
|---|---|
| Age | 1years - 95years |
| Treatment | Glioma groups based on molecular pathology or genetic variation |
| Clinical Study Identifier | NCT04216537 |
| Sponsor | The First Affiliated Hospital of Zhengzhou University |
| Last Modified on | 19 February 2024 |
How to participate?
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Department of Neurosurgery, First Affiliated Hospital of Zhengzhou University
Zhengzhou China
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Zhenyu Zhang, Dr.
Primary Contact
Department of Neurosurgery, First Affiliated Hospital of Zhengzhou University
Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
Learn moreIf you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
Learn moreComplete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.
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