A Comparison Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy

  • STATUS
    Recruiting
  • End date
    Dec 31, 2028
  • participants needed
    200
  • sponsor
    The Second Hospital of Shandong University
Updated on 19 February 2024
cancer
esophageal cancer
esophagectomy
ivor
thoracic surgery
esophagus cancer

Summary

Surgery is still the main treatment for esophageal cancer, however, the complication and mortality rate of open esophagectomy is high. As a result, the thoracoscopic- laparoscopic minimally invasive esophagectomy (MIE) was developed. The MIE mainly comprised two surgical

approaches

MIE McKeown approach (cervical anastomosis) and MIE Ivor-Lewis approach (intrathoracicanastomosis). The MIE with intrathoracic anastomosis (Ivor-Lewis) is increasingly used for the treatment of mid and lower esophageal cancers. Our study is trying to compare the safety, feasibility, and short-term and long- term outcomes between MIE Ivor-Lewis approach and MIE McKeown approach for the treatment of lower thoracic esophageal cancer and esophageal- gastric junction.

Details
Condition Esophageal Diseases, Esophageal Cancer, Esophageal Cancer, head and neck cancer, head and neck cancer
Age 30years - 80years
Treatment MIE Ivor- Lewis, MIE McKeown
Clinical Study IdentifierNCT04217239
SponsorThe Second Hospital of Shandong University
Last Modified on19 February 2024

Eligibility

Yes No Not Sure

Inclusion Criteria

(I) Patients with clinically staged T1-3N0-2M0 tumors; good cardiopulmonary
function
(II) Patients with lower thoracic esophageal tumors and esophageal- gastric
junction tumor
(III) Patients without a previous history of cancer
(IV) Patients without a previous history of neck or chest surgery

Exclusion Criteria

(I) cardiopulmonary function not good enough for surgery
(II) Patients with hybrid MIE
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Yunpeng

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Yunpeng Zhao

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