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Paclitaxel for the Treatment of Gastric or Gastroesophageal Cancer

Trying Paclitaxel for stomach or gastroesophageal cancer treatment study.

Recruiting
18 years and older
All
Phase 1

Study on Gastric or Gastroesophageal Cancer Treatment

This study is looking at a medication called paclitaxel for people with gastric (stomach) or gastroesophageal cancer. The goal is to find the best dose of this medication and understand its side effects. Paclitaxel is a type of chemotherapy which helps stop cancer cells from growing and spreading.

Key Points:

  • Length of Study: Patients receive treatment weekly for 6 weeks, followed by check-ups every 6 months for 5 years.
  • Who Can Join: Adults with gastric or gastroesophageal cancer, specific blood counts, and no serious infections or heart issues.
  • Time Commitment: Weekly visits for treatment during specified weeks, with long-term follow-up required.

Eligibility: You must have proof of certain types of cancer and completed prior chemotherapy. Women must not be pregnant, and all participants must use birth control. You cannot join if you have certain heart issues, infections, or allergies to chemotherapy.

If you think this study could be right for you or someone you care for, please consider discussing it with a healthcare provider.

Study details
    Abdominal Neoplasm
    Abdominal Cancer
    Neoplasm of unspecified nature of digestive system
    Abdominal Cancer
    Clinical Stage IV Gastric Cancer AJCC v8
    Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
    Clinical Stage IVA Gastric Cancer AJCC v8
    Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
    Clinical Stage IVB Gastric Cancer AJCC v8
    Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
    Metastatic Gastric Adenocarcinoma
    Metastatic Gastroesophageal Junction Adenocarcinoma
    Pathologic Stage IV Gastric Cancer AJCC v8
    Pathologic Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
    Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
    Pathologic Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
    Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8
    Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
    Postneoadjuvant Therapy Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
    Postneoadjuvant Therapy Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8

NCT04220827

M.D. Anderson Cancer Center

19 February 2024

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