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ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease

Trial testing BBB disruption for Alzheimer's treatment.

Recruiting
50-85 years
All
Phase N/A

Study Purpose: This study aims to test the safety and effectiveness of using a tool called the ExAblate Model 4000 to open the blood-brain barrier (BBB) in people with probable Alzheimer's Disease (AD). The blood-brain barrier is like a gatekeeper, controlling what can go from the blood into the brain.

Study Details: Participants in this study will have three procedures using the ExAblate system. This study will take place in up to 4 locations in the U.S. and include up to 10 participants. The study will involve several visits to the study site over a period of time.

  • Length of Study: Involves multiple visits for procedures.
  • Participant Requirements: Must be 50-85 years old, have probable Alzheimer's Disease, and be able to communicate during procedures.
  • Exclusions: Cannot participate if you have certain medical conditions like heart issues, liver disease, or are part of another research study.

Note: This study is not for those who have a history of seizures or certain other health conditions. Reach out to the study team for more detailed information if interested.

Study details
    Alzheimer's Disease

NCT03671889

InSightec

9 May 2025

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