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Effects of Obesity on Autophagy and mTORC1 Signalling in Skeletal Muscle

How obesity affects muscle cell processes and signaling pathways.

Recruiting
18-45 years
All
Phase N/A

We are conducting a research study to understand how muscle growth processes work differently in lean individuals compared to those with obesity. We are looking for participants aged 18-45 years old. You need to have a stable weight and meet the UK physical activity guidelines. Unfortunately, if you have certain conditions like diabetes, kidney disease, or if you are pregnant, you cannot join. You will do a one-time exercise session and drink a protein shake. Muscle and blood samples will be taken to study muscle reactions. The study involves one visit lasting around 3-4 hours.

  • **Age Requirement**: 18-45 years.
  • **Time Commitment**: 1 visit, lasting around 3-4 hours.
  • **Exclusions**: Certain health conditions, medications, and dietary restrictions.
Study details
    Overweight and Obese Adults

NCT07774676

University of Birmingham

20 August 2026

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