Study Purpose: This research aims to explore how certain substances in the blood, called biomarkers (like Fetuin-A and COMP), relate to knee osteoarthritis (a disease where the knee joint wears down over time).
Eligibility: We are looking for two groups of people. The first group should have knee osteoarthritis, specifically classified as Grade 2, 3, or 4. You should not have had any major knee injuries, surgeries, or other serious joint problems. The second group should be healthy volunteers without any joint issues.
Study Details: You will need to visit the research center for some tests and evaluations. This includes X-rays and answering questions about pain and mobility. A fasting blood sample will also be taken to study the levels of Fetuin-A and COMP. The whole study may take several visits but will help us understand knee osteoarthritis better.
- The study lasts for a few months, with multiple visits required.
- Participants will undergo X-rays and provide blood samples.
- Participants include those with knee osteoarthritis and healthy individuals.