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A Feasibility and Safety Study of Intratumoral Diffusing Alpha Radiation Emitters for the Treatment of Advanced Pancreatic Cancer

Testing new treatment for advanced pancreatic cancer safety and feasibility.

Recruiting
18 years and older
All
Phase N/A

This research is for adults 18 years or older with advanced pancreatic cancer. We're studying a special device called "DaRT" that uses tiny seeds to release radiation directly into the tumor. This study lasts about 3 months, with regular check-ups after the DaRT seeds are placed. You will need to visit the study site several times during this period. The goal is to see if this treatment is safe and workable.

To join, you must have a pancreatic tumor that can't be removed by surgery. You should be finished with or unable to continue chemotherapy. It's important that your tumor can be treated with the DaRT seeds. You also need to be in good enough health to participate, with tests showing your body can handle the treatment.

  • Study Length: 3 months of follow-up visits after DaRT procedure.
  • Eligibility: Pancreatic cancer that's advanced and not removable by surgery.
  • Visits: Several check-ups over the 3 months to ensure safety and progress.
Study details
    Pancreatic Cancer
    Unresectable Pancreatic Cancer
    Metastatic Pancreatic Cancer
    Pancreatic Adenocarcinoma

NCT05657743

Alpha Tau Medical LTD.

24 November 2025

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