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Sequential CAR-T Cells Targeting BCMA/GPRC5D in Patients With Relapsed/ Refractory Multiple Myeloma

Testing new CAR-T cells for hard-to-treat multiple myeloma.

Recruiting
21-90 years
All
Phase 1/2

This study looks at a special type of treatment called CAR-T cell therapy for people with a blood cancer called Multiple Myeloma that has come back or not responded to treatment. CAR-T cells are like tiny robots made from your own immune cells that are designed to attack cancer. This study will test how safe and effective these cells are when targeting certain proteins in the cancer cells.

  • Age Criteria: Must be an adult with relapsed/refractory Multiple Myeloma.
  • Time Commitment: The study involves multiple visits over a period of time, but exact details on length are not provided.
  • Key Points: Participants should not have any other cancers or serious heart, liver, or kidney problems and should not be pregnant or planning pregnancy soon.

To be eligible, your liver, kidney, and heart must function well, and you should not have any serious infections or mental disorders. If interested, you need to understand and agree to the study terms.

Study details
    Multiple Myeloma
    Multiple Myeloma in Relapse
    Multiple Myeloma Progression
    Multiple Myeloma
    Refractory

NCT07032129

Essen Biotech

24 November 2025

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