PIVKA-II for Predicting Portal Vein Thrombosis in Hepatocellular Carcinoma
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- STATUS
- Recruiting
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- End date
- Dec 31, 2025
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- participants needed
- 116
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- sponsor
- Tanta University
Summary
The goal of this cross-sectional observational study is to evaluate the relation between Prothrombin induced by vitamin K absence II (PIVKA-II) and the presence of portal vein tumor thrombosis (PVTT) in hepatocellular carcinoma (HCC) patients.
Researchers will compare PIVKA-II serum levels in HCC patients with PVTT and without PVTT.
Participants will undergo history-taking, clinical examination, laboratory investigations, PIVKA-II serum level, Child-Pugh classification, Model for End-stage Liver Disease (MELD) score, BCLC staging, abdominal ultrasonography, and Triphasic CT abdomen with contrast or MRI to evaluate tumor site, size, number, and presence of PVTT (a filling defect in the portal vein or its branch to distinguish PVTT or thrombus).
Details
| Condition | Hepato Cellular Carcinoma (HCC), Portal Vein Tumour Thrombosis |
|---|---|
| Age | 18years or above |
| Clinical Study Identifier | NCT06960954 |
| Sponsor | Tanta University |
| Last Modified on | 8 May 2025 |
How to participate?
Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
Learn moreIf you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
Learn moreComplete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.
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