This clinical trial is for people aged 18 to 69 with systemic sclerosis, a rare condition causing thick skin and other health issues. The study examines if a special medication can help treat fingertip wounds caused by this illness. Participants might receive one or two applications of this investigational medication or a placebo, which looks like the medication but contains no active drug. The study will last up to 31 days, during which participants will visit the clinic up to 8 times, with 2 visits possibly done by phone.

To join, you must:

• Have at least one fingertip wound related to systemic sclerosis.
• Be able to understand and follow study instructions.
• Not have severe complications like infections or serious organ issues.

The study will check for any side effects and see if the investigational medication affects blood flow, pain, or other symptoms. Participants will help researchers by answering questions and keeping a diary about their symptoms.