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Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis

Researching Frexalimab's effects in adults with nonrelapsing secondary progressive MS.

Recruiting
18-60 years
All
Phase 3

Study Overview: This research is looking at how safe and effective an investigational medication is for adults with a type of multiple sclerosis (MS) called nonrelapsing secondary progressive MS (nrSPMS). MS is a disease where the immune system attacks the protective covering of nerves. This can cause problems with movement and vision.

Who Can Join? Adults aged 18 to 60 with a past diagnosis of relapsing-remitting MS (RRMS) and current diagnosis of secondary progressive MS (SPMS) can join if they've shown disability progression in the last year and haven't had relapses for 2 years. They must have a specific disability score and use birth control if required by local rules.

Study Details:

  • Duration: The study lasts between 27 to 51 months.
  • Visits: Up to 27 visits are needed, starting monthly, then every 3 months.
  • Note: Participants cannot have certain other diseases, infections, or allergies, and must not have used the investigational medication before.

Consider joining if you meet the criteria and wish to contribute to MS research.

Study details
    Multiple Sclerosis

NCT06141486

Sanofi

4 March 2025

Step 1
Check your eligibility
Take up this questionnaire to help us determine if you have symptoms that are common to this clinical study. If you have the common symptoms, you may be eligible to take part in the study.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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