This study is for people with Alport Syndrome, a genetic condition affecting the kidneys, ears, and eyes. The research aims to see if an investigational medication can help slow kidney damage and is safe for patients. Participants will join for about 110 weeks, almost two years. This time includes a four-week screening, 48 weeks with either the medication or a placebo (a pill with no effect), another 48 weeks with the actual medication, and a 10-week follow-up.
To be eligible, you need to:
- Be between 18-55 years old with a confirmed diagnosis of Alport Syndrome.
- Have kidney function within a specific range (eGFR between 35 and 90), a measure of how well your kidneys work.
- Not have other major kidney diseases or conditions affecting drug absorption.
Participants must agree to certain lifestyle rules, like using birth control if applicable. This study requires several visits to the clinic, and you should be comfortable with this commitment.