Ambulance Calls for Substance Use and Alcohol in a Pandemic (ASAP)
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- STATUS
- Recruiting
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- participants needed
- 55000
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- sponsor
- University of Lincoln
Summary
The Primary objective is to explore ambulance service attendance at incidents involving
Description
The Primary objective is to explore ambulance service attendance at incidents involving
A time series analysis will be conducted to examine the calls over the course of the year prior to the lockdown, and then compare this to the period of lockdown and following months. This will use the 'Interrupted Time Series' (ITS) approach. To explore this regression models will be built that examine the causal models for attendance prior to the pandemic and compared to the lockdown time frame.
A multivariable regression model will be built. Initially a Directed Acyclic Graph (DAG) will allow the identification of confounders and exposures relevant to the model. A logistic regression model will be used to calculate the relative risk of call during lockdown compared to the data prior to lockdown. The model will be fit using p<0.05 as the definition of statistical significance.
Descriptive statistics, trend analysis and predictive analysis will be conducted on the data
set to determine trends across time, factors that predict patients requiring ambulance
attendance, and factors that predict treatment outcomes. Missing data will be examined for
systematic bias, and where found to be missing at random will be excluded from analysis.
Where not missing at random,
Analysis will examine covariates. Age will be defined as single year continuous variable and examined in categories such as 5-year age groups. Ethnicity will be categorised as groups, such as black, Asian, other minority and mixed ethnic groups will be explored. Census data such as the deprivation, rurality, income, employment, disability and education will look at the decile as defined.
Details
| Condition |
Emergencies [Disease/Finding], Therapeutic procedure, treatment, |
|---|---|
| Age | 100years or below |
| Treatment | attendance by ambulance crew |
| Clinical Study Identifier | NCT04474444 |
| Sponsor | University of Lincoln |
| Last Modified on | 19 February 2024 |
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
Learn moreIf you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
Learn moreComplete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.
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