Myotonia and Muscle Stiffness in NMD
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- STATUS
- Recruiting
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- participants needed
- 90
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- sponsor
- Klinikum der Universitaet Muenchen
Summary
The primary objective of this study is to assess stiffness, muscle tone, relaxation periods and elasticity of various muscles in patients with dystrophic or non-dystrophic myotonia. The secondary objectives are (1) to provide reference values for stiffness, muscle tone, relaxation periods and elasticity of various muscles in patients with dystrophic or non-dystrophic myotonia; to provide reference values for stiffness, muscle tone, relaxation periods and elasticity of various muscles in patients with non-myotonic neuromuscular disorders, (3) assess correlations between to compare result values for stiffness, muscle tone, relaxation periods and elasticity with clinical muscle function tests, measured by clinical evaluation (MRC-scale) and the 6-minute walk test; (4) assess correlations between subcutaneous fat and muscle thickness and echogenicity, measured by muscle ultrasound and result values for stiffness, muscle tone, relaxation periods and elasticity.
Details
| Condition | Amyotonia Congenita |
|---|---|
| Age | 18-100 years |
| Treatment | MyotonPro, Six-minute walk test, Semiquantitative muscle ultrasound, Hand-held Dynamometry of muscle strength |
| Clinical Study Identifier | NCT04411732 |
| Sponsor | Klinikum der Universitaet Muenchen |
| Last Modified on | 19 February 2024 |
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